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Article

BIK1, a protein required for microtubule function during mating and mitosis in Saccharomyces cerevisiae, colocalizes with tubulin.

The Journal of cell biology - 1 Dec 1990

Berlin V, Styles C A, Fink G R

Abstract excerpt

BIK1 function is required for nuclear fusion, chromosome disjunction, and nuclear segregation during mitosis. The BIK1 protein colocalizes with tubulin to the spindle pole body and mitotic spindle. Synthetic lethality observed in double mutant strains containing a mutation in the BIK1 gene and in the gene for alpha- or beta-tubulin is consistent with a physical interaction between BIK1 and tubulin. Furthermore,...

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Identifiers

PMID: 2277073
DOI: 10.1083/jcb.111.6.2573
PMCID: PMC2116401

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