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Article

Intragenic anaplastic lymphoma kinase (ALK) rearrangements: translocations as a novel mechanism of ALK activation in neuroblastoma tumors.

Genes, chromosomes & cancer - 1 Feb 2015

Fransson Susanne, Hansson Magnus, Ruuth Kristina, Djos Anna, Berbegall Ana, Javanmardi Niloufar, Abrahamsson Jonas, Palmer Ruth H, Noguera Rosa, Hallberg Bengt, Kogner Per, Martinsson Tommy

Abstract excerpt

Anaplastic lymphoma kinase (ALK) has been demonstrated to be deregulated in sporadic as well as in familiar cases of neuroblastoma (NB). Whereas ALK-fusion proteins are common in lymphoma and lung cancer, there are few reports of ALK rearrangements in NB indicating that ALK mainly exerts its onco...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25251827
DOI: 10.1002/gcc.22223

Genes

ALK
MYCN
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25251827-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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