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Article

Characterization of oxygen-induced retinopathy in mice carrying an inactivating point mutation in the catalytic site of ADAM15.

Investigative ophthalmology & visual science - 23 Sept 2014

Maretzky Thorsten, Blobel Carl P, Guaiquil Victor

Abstract excerpt

PURPOSE: Retinal neovascularization is found in diseases such as macular degeneration, diabetic retinopathy, or retinopathy of prematurity and is usually caused by alterations in oxygen supply. We have previously described that mice lacking the membrane-anchored metalloproteinase ADAM15 (a Disintegrin and Metalloprotease 15) have decreased pathological neovascularization of the retina in the oxygen-induced...

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Source

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Identifiers

PMID: 25249606
DOI: 10.1167/iovs.14-14472
PMCID: PMC4209716

Genes

ADAM15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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