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Article

ADAM9 Is Involved in Pathological Retinal Neovascularization

10 Mar 2009

Abstract excerpt

Pathological ocular neovascularization, caused by diabetic retinopathy, age-related macular degeneration, or retinopathy of prematurity, is a leading cause of blindness, yet much remains to be learned about its underlying causes. Here we used oxygen-induced retinopathy (OIR) and laser-induced choroidal neovascularization (CNV) to assess the contribution of the metalloprotease-disintegrin ADAM9 to ocular...

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PMID: 19273593
DOI: 10.1128/mcb.01460-08

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