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Article

Müller cell‐derived VEGF is a significant contributor to retinal neovascularization

11 Aug 2009

Abstract excerpt

Vascular endothelial growth factor (VEGF-A) is a major pathogenic factor and a therapeutic target for age-related macular degeneration, diabetic retinopathy, and retinopathy of prematurity. Despite intensive effort in the field, the cellular mechanisms of VEGF action remain virtually uninvestigated. This situation makes it difficult to design cellular target-based therapeutics for these diseases. In light of the...

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PMID: 19768732
DOI: 10.1002/path.2611

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