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A label-free signal amplification assay for DNA detection based on exonuclease III and nucleic acid dye SYBR Green I.

Talanta - 30 Sept 2013

Zheng Aihua, Luo Ming, Xiang Dongshan, Xiang Xia, Ji Xinghu, He Zhike

Abstract excerpt

We have developed a new fluorescence method for specific single-stranded DNA sequences with exonuclease III (Exo III) and nucleic acid dye SYBR Green I. It is demonstrated by a reverse transcription oligonucleotide sequence (target DNA, 27 bases) of RNA fragment of human immunodeficiency virus (HIV) as a model system. In the absence of the target DNA, the hairpin-probe is in the stem-closed structure, the...

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PMID: 23953440
DOI: 10.1016/j.talanta.2013.03.080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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