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Article

Non-Covalent Fluorescent Labeling of Hairpin DNA Probe Coupled with Hybridization Chain Reaction for Sensitive DNA Detection.

Applied spectroscopy - 1 Apr 2016

Song Luna, Zhang Yonghua, Li Junling, Gao Qiang, Qi Honglan, Zhang Chengxiao

Abstract excerpt

An enzyme-free signal amplification-based assay for DNA detection was developed using fluorescent hairpin DNA probes coupled with hybridization chain reaction (HCR). The hairpin DNAs were designed to contain abasic sites in the stem moiety. Non-covalent labeling of the hairpin DNAs was achieved when a fluorescent ligand was bound to the abasic sites through hydrogen bonding with the orphan cytosine present on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26879193
DOI: 10.1177/0003702816631305

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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