Article
Haplotype analyses of DNA repair gene polymorphisms and their role in ulcerative colitis.
PloS one - 1 Jan 2014
Bardia Avinash, Tiwari Santosh K, Vishwakarma Sandeep K, Habeeb Md Aejaz, Nallari Pratibha, Sultana Shaik A, Pasha Shaik A, Reddy Yugandhar P, Khan Aleem A
Abstract excerpt
Ulcerative colitis (UC) is a major clinical form of inflammatory bowel disease. UC is characterized by mucosal inflammation limited to the colon, always involving the rectum and a variable extent of the more proximal colon in a continuous manner. Genetic variations in DNA repair genes may influence the extent of repair functions, DNA damage, and thus the manifestations of UC. This study thus evaluated the role of...
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