Article
[The associations of methylenetetrahydrofolate reductase gene C677T and A1298C polymorphisms and ulcerative colitis].
Zhonghua nei ke za zhi - 1 May 2011
Xu Chang-long, Lin Xiu-qing, Lan De-yun, Wang Jian-zhang, Zheng Bo, Xue Zhan-xiong
Abstract excerpt
OBJECTIVE: To investigate the association between the genetic polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and ulcerative colitis (UC) of Han ethnic population in Zhejiang, China. METHODS: Two hundred and seventy-four consecutive patients with UC and 726 healthy controls (HC) were studied. The genetic polymorphisms of MTHFR (C677T and A1298C) were genotyped using PCR-RELP methods. RESULTS: The...
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