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Article

Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2014

Yu Chun I, Becker Christian, Metang Patrick, Marches Florentina, Wang Yuanyuan, Toshiyuki Hori, Banchereau Jacques, Merad Miriam, Palucka A Karolina

Abstract excerpt

Dendritic cells (DCs) play the central role in the priming of naive T cells and the differentiation of unique effector T cells. In this study, using lung tissues and blood from both humans and humanized mice, we analyzed the response of human CD1c(+) and CD141(+) DC subsets to live-attenuated influenza virus. Specifically, we analyzed the type of CD4(+) T cell immunity elicited by live-attenuated influenza...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25246496
DOI: 10.4049/jimmunol.1401159
PMCID: PMC4201960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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