Article

GM-CSF-activated human dendritic cells promote type1 T follicular helper cells (Tfh1) polarization in a CD40-dependent manner

2022-04-28

Abstract excerpt

T follicular helper (Tfh) cells are specialized CD4 + T cells that regulate humoral immunity by providing B cell help. Tfh1 sub-population was recently identified and associated with severity in infection and autoimmune diseases. The cellular and molecular requirements to induce human Tfh1 differentiation are unknown. Our work investigated the role of human dendritic cells (DC) in promoting Tfh1 differentiation a...

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Literature Corpus work: c94576ff-c484-5240-83f4-1b997b733116
DOI: 10.1101/2022.04.28.489850

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GM-CSF-activated human dendritic cells promote type1 T follicular helper cells (Tfh1) polarization in a CD40-dependent mannerDOI 10.1101/2022.04.28.489850Read

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