Article
Quality control method for RNA-seq using single nucleotide polymorphism allele frequency.
Genes to cells : devoted to molecular & cellular mechanisms - 1 Nov 2014
Endo Takaho A
Abstract excerpt
RNA sequencing (RNA-seq) provides information not only about the level of expression of individual genes but also about genomic sequences of host cells. When we use transcriptome data with whole-genome single nucleotide polymorphism (SNP) variant information, the allele frequency can show the genetic composition of the cell population and/or chromosomal aberrations. Here, I show how SNPs in mRNAs can be used to...
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