Article

Estimating allele-specific expression of SNVs from 10x Genomics Single-Cell RNA-Sequencing Data

2019-12-23

Abstract excerpt

With the recent advances in single-cell RNA-sequencing (scRNA-seq) technologies, estimation of allele expression from single cells is becoming increasingly reliable. Allele expression is both quantitative and dynamic and is an essential component of the genomic interactome. Here, we systematically estimate allele expression from heterozygous single nucleotide variant (SNV) loci using scRNA-seq data generated on th...

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Literature Corpus work: df7daa7d-2750-5db8-92f2-736d53c1da56
DOI: 10.1101/2019.12.22.886119

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