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Article

Transgenic mouse model of X-linked cleft palate.

Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Feb 1993

Wilson J B, Ferguson M W, Jenkins N A, Lock L F, Copeland N G, Levine A J

Abstract excerpt

A transgenic mouse line, PyLMP.5, exhibited a sex-linked lethality not observed in any other lines expressing the transgene. In this unique line, the transgene integrated into the X chromosome, yielding a simple tandem duplication of the insert sequences with minimal, if any, additional rearrangement of the cellular sequences. The predominant phenotype was a cleft secondary palate and neonatal lethality in males....

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PMID: 8494785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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