Article
[New aspects of genetics and molecular mechanisms on thyroid morphogenesis for the understanding of thyroid dysgenesia].
Arquivos brasileiros de endocrinologia e metabologia - 1 Dec 2008
Ramos Helton E, Nesi-França Suzana, Maciel Rui M B
Abstract excerpt
The elucidation of the molecular mechanisms underlying the very early steps of thyroid organogenesis and the etiology of most cases of thyroid dysgenesis are poorly understood. Many genes have been identified as important contributors to survival, proliferation and migration of thyroid cells precursors, acting as an integrated and complex regulatory network. Moreover, by generation of mouse mutants, the studies...
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