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Article

High-throughput knock-in coupling gene targeting with the HPRT minigene and Cre-mediated recombination.

Genesis (New York, N.Y. : 2000) - 1 Dec 2008

Kim Tae Moon, Choi Yong Jun, Ko Jun Ho, Hasty Paul

Abstract excerpt

Single nucleotide polymorphisms (SNPs) may influence protein function possibly contributing to phenotype; yet, for most SNPs their potential influence is unknown. Here, we present a technique in mouse embryonic stem cells that enables high-throughput knock-in (the placement of coding sequences ad...

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PMID: 18932256
DOI: 10.1002/dvg.20439

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18932256-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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