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Article

Exposure of Phosphatidylserine by Xk-related Protein Family Members during Apoptosis

18 Sept 2014

Abstract excerpt

Apoptotic cells expose phosphatidylserine (PtdSer) on their surface as an "eat me" signal. Mammalian Xk-related (Xkr) protein 8, which is predicted to contain six transmembrane regions, and its Caenorhabditis elegans homolog CED-8 promote apoptotic PtdSer exposure. The mouse and human Xkr families consist of eight and nine members, respectively. Here, we found that mouse Xkr family members, with the exception of...

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PMID: 25231987
DOI: 10.1074/jbc.m114.583419

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