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Article

Analysis of the evolution and structure of a complex intrahost viral population in chronic hepatitis C virus mapped by ultradeep pyrosequencing.

Journal of virology - 1 Dec 2014

Palmer Brendan A, Dimitrova Zoya, Skums Pavel, Crosbie Orla, Kenny-Walsh Elizabeth, Fanning Liam J

Abstract excerpt

UNLABELLED: Hepatitis C virus (HCV) causes chronic infection in up to 50% to 80% of infected individuals. Hypervariable region 1 (HVR1) variability is frequently studied to gain an insight into the mechanisms of HCV adaptation during chronic infection, but the changes to and persistence of HCV subpopulations during intrahost evolution are poorly understood. In this study, we used ultradeep pyrosequencing (UDPS)...

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Source

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Identifiers

PMID: 25231312
DOI: 10.1128/JVI.01732-14
PMCID: PMC4248971

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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