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Article

High-Resolution Evolutionary Analysis of Within-Host Hepatitis C Virus Infection.

The Journal of infectious diseases - 5 May 2019

Raghwani Jayna, Wu Chieh-Hsi, Ho Cynthia K Y, De Jong Menno, Molenkamp Richard, Schinkel Janke, Pybus Oliver G, Lythgoe Katrina A

Abstract excerpt

BACKGROUND: Despite recent breakthroughs in treatment of hepatitis C virus (HCV) infection, we have limited understanding of how virus diversity generated within individuals impacts the evolution and spread of HCV variants at the population scale. Addressing this gap is important for identifying the main sources of disease transmission and evaluating the risk of drug-resistance mutations emerging and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30602023
DOI: 10.1093/infdis/jiy747
PMCID: PMC6500553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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