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Article

Association of Promoter Methylation of RUNX3 Gene with the Development of Esophageal Cancer: A Meta Analysis

17 Sept 2014

Abstract excerpt

BACKGROUND: Runt-related transcription factor 3 (RUNX3) is a member of the runt-domain family of transcription factors. Emerging evidence indicates that RUNX3 is a tumor suppressor gene in several types of human cancers including esophageal cancer. However, the association between RUNX3 promoter methylation and esophageal cancer remains unclear. Here we conducted a systematic review and meta-analysis to...

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PMID: 25229459
DOI: 10.1371/journal.pone.0107598

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