Article
Genetic variants in the Runt-related transcription factor 3 gene contribute to gastric cancer risk in a Chinese population.
Cancer science - 1 Sept 2009
Wu Dongmei, Tian Yuanyuan, Gong Weida, Zhu Haixia, Zhang Zhizhong, Wang Meilin, Wang Shizhi, Tan Ming, Wu Haorong, Zhang Zhengdong
Abstract excerpt
Runt-related transcription factor 3 (RUNX3) is a well known gene for its functions in gastric cancer suppression, but the effect of its genetic variations on the risk of gastric cancer remains unclear. In this study, ten tagging single nucleotide polymorphisms (tSNPs) of the RUNX3 gene were selected and genotyped in a hospital-based case-control study of 312 gastric cancer patients and 329 cancer-free controls in...
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