Article
p 53 codon 72 polymorphism in stomach and colorectal adenocarcinomas in Iranian patients.
Indian journal of cancer - 1 Jan 2000
Mojtahedi Z, Haghshenas M R, Hosseini S V, Fattahi M J, Ghaderi A
Abstract excerpt
BACKGROUND: The association of a functional single nucleotide polymorphism at codon 72 of the p53 gene (Arg72Pro) with malignancy is a subject of controversy. We analyzed this polymorphism in 224 patients with gastrointestinal cancers (92 with stomach cancer and 132 with colorectal cancer) and in 163 healthy controls. MATERIAL AND METHODS: DNA was extracted from peripheral blood mononuclear cells and amplified...
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