Article
Updated meta-analysis of the TP53 Arg72Pro polymorphism and gastric cancer risk.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2012
Xiang Bin, Mi Yuan-Yuan, Li Teng-Fei, Liu Peng-Fei
Abstract excerpt
OBJECTIVE: The p53 tumor suppressor pathway plays an important role in gastric cancer (GC) development. Auto-regulatory feedback control of p53 expression is critical to maintaining proper tumor suppressor function. So far, several studies between p53 Arg72Pro polymorphism and GC have generated controversial and inconclusive results. METHODS: To better assess the purported relationship, we performed a...
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