Article
A characteristic bent conformation of RNA pseudoknots promotes -1 frameshifting during translation of retroviral RNA.
Journal of molecular biology - 26 Jul 1996
Chen X, Kang H, Shen L X, Chamorro M, Varmus H E, Tinoco I
Abstract excerpt
The structures of four different RNA pseudoknots that provide one of the signals required for ribosomal frameshifting in mouse mammary tumor virus have been determined by NMR. The RNA pseudoknots have similar sequences and assume similar secondary structures, but show significantly different fram...
Topics
- Base Sequence
- Magnetic Resonance Spectroscopy
- Mammary Tumor Virus, Mouse
- Models, Molecular
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Protein Biosynthesis
- RNA, Viral
- Retroviruses, Simian