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Article

Environmental particulate (PM2.5) augments stiffness-induced alveolar epithelial cell mechanoactivation of transforming growth factor beta.

PloS one - 1 Jan 2014

Dysart Marilyn M, Galvis Boris R, Russell Armistead G, Barker Thomas H

Abstract excerpt

Dysfunctional pulmonary homeostasis and repair, including diseases such as pulmonary fibrosis (PF), chronic obstructive pulmonary disease (COPD), and tumorigenesis have been increasing over the past decade, a fact that heavily implicates environmental influences. Several investigations have suggested that in response to increased transforming growth factor--beta (TGFβ) signaling, the alveolar type II (ATII)...

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Identifiers

PMID: 25226160
DOI: 10.1371/journal.pone.0106821
PMCID: PMC4167324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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