Article
Synergistic effects of particulate matter and substrate stiffness on epithelial-to-mesenchymal transition.
Research report (Health Effects Institute) - 1 Nov 2014
Barker Thomas H, Dysart Marilyn M, Brown Ashley C, Douglas Alison M, Fiore Vincent F, Russell Armistead G
Abstract excerpt
Dysfunctional pulmonary homeostasis and repair, including diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease (COPD*), and tumorigenesis, have been increasing steadily over the past decade, a fact that heavily implicates environmental influences. Several investigations have suggested that the lung "precursor cell"--the alveolar type II (ATII) epithelial cell--is central in the initiation...
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