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Article

The Asp84Glu variant of the melanocortin 1 receptor (MC1R) is associated with melanoma.

Human molecular genetics - 1 Oct 1996

Valverde P, Healy E, Sikkink S, Haldane F, Thody A J, Carothers A, Jackson I J, Rees J L

Abstract excerpt

Melanocyte stimulating hormone (MSH) plays an important role in determining the cutaneous response to ultraviolet radiation and may also influence melanoma progression. We have previously shown that variants of the melanocortin receptor present on melanocytes, MC1R, are associated with sun sensitivity and red hair in a UK population and therefore now consider the gene as a candidate for melanoma susceptibility....

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Identifiers

PMID: 8894704
DOI: 10.1093/hmg/5.10.1663

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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