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Article

Control of replication initiation by the Sum1/Rfm1/Hst1 histone deacetylase.

BMC molecular biology - 6 Nov 2008

Weber Jan M, Irlbacher Horst, Ehrenhofer-Murray Ann E

Abstract excerpt

BACKGROUND: Replication initiation at origins of replication in the yeast genome takes place on chromatin as a template, raising the question how histone modifications, for instance histone acetylation, influence origin firing. Initiation requires binding of the replication initiator, the Origin Recognition Complex (ORC), to a consensus sequence within origins. In addition, other proteins bind to recognition...

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Identifiers

PMID: 18990212
DOI: 10.1186/1471-2199-9-100
PMCID: PMC2585588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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