Article
Regulation of mitotic spindle disassembly by an environmental stress-sensing pathway in budding yeast.
Genetics - 1 Nov 2014
Pigula Adrianne, Drubin David G, Barnes Georjana
Abstract excerpt
Timely spindle disassembly is essential for coordination of mitotic exit with cytokinesis. In the budding yeast Saccharomyces cerevisiae, the microtubule-associated protein She1 functions in one of at least three parallel pathways that promote spindle disassembly. She1 phosphorylation by the Aurora kinase Ipl1 facilitates a role for She1 in late anaphase, when She1 contributes to microtubule depolymerization and...
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