Article
Nim1-related kinases coordinate cell cycle progression with the organization of the peripheral cytoskeleton in yeast.
Genes & development - 15 Jan 1999
Barral Y, Parra M, Bidlingmaier S, Snyder M
Abstract excerpt
The mechanisms that couple cell cycle progression with the organization of the peripheral cytoskeleton are poorly understood. In Saccharomyces cerevisiae, the Swe1 protein has been shown previously to phosphorylate and inactivate the cyclin-dependent kinase, Cdc28, thereby delaying the onset of mitosis. The nim1-related protein kinase, Hsl1, induces entry into mitosis by negatively regulating Swe1. We have found...
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