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Article

DNA methylation changes in the postmortem dorsolateral prefrontal cortex of patients with schizophrenia

26 Aug 2014

Abstract excerpt

BACKGROUND: Schizophrenia is a complex psychiatric disorder with a lifetime morbidity rate of 0.5-1.0%. The pathophysiology of schizophrenia still remains obscure. Accumulating evidence indicates that DNA methylation, which is the addition of a methyl group to the cytosine in a CpG dinucleotide, might play an important role in the pathogenesis of schizophrenia. METHODS: To gain further insight into the molecular...

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PMID: 25206360
DOI: 10.3389/fgene.2014.00280

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