Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune evasion through competitive inhibition: the shielding effect of cancer non-stem cells.

Journal of theoretical biology - 7 Jan 2015

Kareva Irina

Abstract excerpt

It has been recently proposed that the two emerging hallmarks of cancer, namely altered glucose metabolism and immune evasion, may in fact be fundamentally linked. This connection comes from up-regulation of glycolysis by tumor cells, which can lead to active competition for resources in the tumor microenvironment between tumor and immune cells. Here it is further proposed that cancer stem cells (CSCs) can...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aerobiosis
Share to Glycolysis
Share to Immune Evasion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity

Share to Models, Immunological

Share to Neoplastic Stem Cells

Share to Oxygen

Share to T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 25195001
DOI: 10.1016/j.jtbi.2014.08.035

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune evasion through competitive inhibition: the shielding effect of cancer non-stem cells.PMID 25195001Read ↗

Tumor microenvironment as niche constructed by cancer stem cells: Breaking the ecosystem to combat cancerSemantic proximity Read ↗

Determinants of stem cell enrichment in healthy tissues and tumors: implications for non-genetic drug resistanceSemantic proximity Read ↗

T cell stemness and dysfunction in tumors are triggered by a common mechanismSemantic proximity Read ↗

Survival of the fittest: Cancer challenges T cell metabolismSemantic proximity Read ↗

Non-stem cancer cell kinetics modulate solid tumor progressionSemantic proximity Read ↗

Linking tumor glycolysis and immune evasion in cancer: Emerging concepts and therapeutic opportunitiesSemantic proximity Read ↗

Computational Modeling to Determine the Effect of Phenotypic Heterogeneity in Tumors on the Collective Tumor-Immune Interactions.Semantic proximity Read ↗

Successful Therapy Must Eradicate Cancer Stem CellsSemantic proximity Read ↗

Synergistic targeting of breast cancer stem-like cells by human γδ T cells and CD8+ T cells.Semantic proximity Read ↗

A novel computational tool for tracking cancer energy hijacking from immune cellsSemantic proximity Read ↗

A model for the intrinsic limit of cancer therapy: Duality of treatment-induced cell death and treatment-induced stemnessSemantic proximity Read ↗

Exosomes Exercise Inhibition of Anti-Tumor Immunity during ChemotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.