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Article

Using Mendelian inheritance to improve high-throughput SNP discovery.

Genetics - 1 Nov 2014

Chen Nancy, Van Hout Cristopher V, Gottipati Srikanth, Clark Andrew G

Abstract excerpt

Restriction site-associated DNA sequencing or genotyping-by-sequencing (GBS) approaches allow for rapid and cost-effective discovery and genotyping of thousands of single-nucleotide polymorphisms (SNPs) in multiple individuals. However, rigorous quality control practices are needed to avoid high levels of error and bias with these reduced representation methods. We developed a formal statistical framework for...

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Identifiers

PMID: 25194160
DOI: 10.1534/genetics.114.169052
PMCID: PMC4224174

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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