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Article

Application of genome-wide single nucleotide polymorphism typing: simple association and beyond.

PLoS genetics - 6 Oct 2006

Gibbs J Raphael, Singleton Andrew

Abstract excerpt

The International HapMap Project and the arrival of technologies that type more than 100,000 SNPs in a single experiment have made genome-wide single nucleotide polymorphism (GW-SNP) assay a realistic endeavor. This has sparked considerable debate regarding the promise of GW-SNP typing to identify genetic association in disease. As has already been shown, this approach has the potential to localize common genetic...

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PMID: 17029559
DOI: 10.1371/journal.pgen.0020150
PMCID: PMC1592240

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