Article
[Relationship between IL-18 gene polymorphism and unexplained recurrent spontaneous abortion].
Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 1 Jul 2014
Wang Dan, Wang Chen, Zheng Ling-zhi, Zhu Min, Zhu Yi-min
Abstract excerpt
OBJECTIVE: To investigate the association between IL-18 polymorphisms and the risk of unexplained recurrent spontaneous abortion (URSA). METHODS: The polymorphism of rs187238, rs360718 and rs360717 in IL-18 was determined by PCR in combination with DNA sequencing in 207 patients with URSA and 144 women with normal pregnancy. RESULTS: The frequency of gene types GG, GC+CC of rs187238 (-137 G/C) in URSA group and...
Read the complete abstract on PubMed