Article
Association between lower frequency of R381Q variant (rs11209026) in IL-23 receptor gene and increased risk of recurrent spontaneous abortion (RSA).
Journal of immunotoxicology - 1 Jan 2015
Abdollahi Elham, Tavasolian Fataneh, Ghasemi Nasrin, Mirghanizadeh Seyed Ali, Azizi Mohammdareza, Ghoryani Mohsen, Samadi Morteza
Abstract excerpt
Recurrent spontaneous abortion (RSA) is defined as three or more consecutive spontaneous abortions before the 20th week of gestation. The purpose of the present study was to investigate the association between a functional single nucleotide polymorphism (SNP) in the interleukin (IL)-23 receptor gene (IL-23R; rs11209026, 1142 G wild type → A reduced function, Arg381Gln, R381Q) and RSA. For the study, 200 RSA...
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