Article
[Association of polymorphisms in signal transducer and activator of transcription 4 gene and the susceptibility to unexplained recurrent spontaneous abortions].
Zhonghua fu chan ke za zhi - 1 Sept 2013
Li Yin-Guang, You Ze-Shan, Wu Zai-Gui, Li Zhu-Yu, Li Jie, Zhang Xiu-Ming, Fang Li-Yuan, Jiang Li
Abstract excerpt
OBJECTIVE: To investigate the association between the polymorphisms of signal transducer and activator of transcription 4 (STAT4) gene and the susceptibility to unexplained recurrent spontaneous abortion(URSA). METHODS: PCR-restriction fragment length polymorphism (PCR-RFLP) was used to detect genotype 3 loca (rs7574865 G/T, rs10181656 C/G and rs16833431 C/T) polymorphism of STAT4 in 246 URSA cases (URSA group)...
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