Article
The variant allele of the rs188140481 polymorphism confers a moderate increase in the risk of prostate cancer in Polish men.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Mar 2015
Antczak Andrzej, Wokołorczyk Dominika, Kluźniak Wojciech, Kashyap Aniruddh, Jakubowska Anna, Gronwald Jacek, Huzarski Tomasz, Byrski Tomasz, Dębniak Tadeusz, Masojć Bartłomiej, Górski Bohdan, Gromowski Tomasz, Gołąb Adam, Sikorski Andrzej, Słojewski Marcin, Gliniewicz Bartłomiej, Borkowski Tomasz, Borkowski Andrzej, Przybyła Jacek, Sosnowski Marek, Małkiewicz Bartosz, Zdrojowy Romuald, Sikorska-Radek Paulina, Matych Józef, Wilkosz Jacek, Różański Waldemar, Kiś Jacek, Bar Krzysztof, Janiszewska Hanna, Stawicka Małgorzata, Milecki Piotr, Lubiński Jan, Narod Steven A, Cybulski Cezary
Abstract excerpt
A number of single nucleotide polymorphisms (SNPs) in the human genome have been associated with increased risk of prostate cancer. Recently, a single SNP in the region of chromosome 8q24 (rs188140481) has been associated with a three-fold increased risk of prostate cancer in Europe and North America. To establish whether rs188140481 is associated with the risk of prostate cancer in Poland, we genotyped 3467 men...
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