Article
Two common chromosome 8q24 variants are associated with increased risk for prostate cancer.
Cancer research - 1 Apr 2007
Wang Liang, McDonnell Shannon K, Slusser Joshua P, Hebbring Scott J, Cunningham Julie M, Jacobsen Steven J, Cerhan James R, Blute Michael L, Schaid Daniel J, Thibodeau Stephen N
Abstract excerpt
Two variants (rs1447295/DG8S737) of chromosome 8q24 were recently reported to be associated with increased risk of prostate cancer (PC). To confirm this finding, we genotyped and compared the frequencies of these polymorphisms among 1,121 Caucasian men with PC (435 men with familial PC, 491 men with sporadic PC, and 195 men with aggressive PC) to 545 population-based controls. For the single nucleotide...
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