Article
Systematic confirmation study of reported prostate cancer risk-associated single nucleotide polymorphisms in Chinese men.
Cancer science - 1 Oct 2011
Liu Fang, Hsing Ann W, Wang Xiang, Shao Qiang, Qi Jun, Ye Yu, Wang Zhong, Chen Hongyan, Gao Xin, Wang Guozeng, Chu Lisa W, Ding Qiang, OuYang Jun, Gao Xu, Huang Yichen, Chen Yanbo, Gao Yu Tang, Zhang Zuo-Feng, Rao Jianyu, Shi Rong, Wu Qijun, Wang Meilin, Zhang Zhengdong, Zhang Yuanyuan, Jiang Haowen, Zheng Jie, Hu Yanlin, Guo Ling, Lin Xiaoling, Tao Sha, Jin Guangfu, Sun Jielin, Lu Daru, Zheng S Lilly, Sun Yinghao, Mo Zengnan, Xu Jianfeng
Abstract excerpt
More than 30 prostate cancer (PCa) risk-associated loci have been identified in populations of European descent by genome-wide association studies. We hypothesized that a subset of these loci might be associated with PCa risk in Chinese men. To test this hypothesis, 33 single nucleotide polymorphisms (SNP), one each from the 33 independent PCa risk-associated loci reported in populations of European descent, were...
Topics
- Asian People
- Biomarkers, Tumor
- Case-Control Studies
- China
- Genetic Variation
- Genome-Wide Association Study
- Genotype
- Humans