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Article

Expansion of stochastic expression repertoire by tandem duplication in mouse Protocadherin-α cluster.

Scientific reports - 2 Sept 2014

Kaneko Ryosuke, Abe Manabu, Hirabayashi Takahiro, Uchimura Arikuni, Sakimura Kenji, Yanagawa Yuchio, Yagi Takeshi

Abstract excerpt

Tandem duplications are concentrated within the Pcdh cluster throughout vertebrate evolution and as copy number variations (CNVs) in human populations, but the effects of tandem duplication in the Pcdh cluster remain elusive. To investigate the effects of tandem duplication in the Pcdh cluster, here we generated and analyzed a new line of the Pcdh cluster mutant mice. In the mutant allele, a 218-kb region...

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Identifiers

PMID: 25179445
DOI: 10.1038/srep06263
PMCID: PMC4151104

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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