Article
Advantageous diversity maintained by balancing selection in humans.
Current opinion in genetics & development - 1 Dec 2014
Key Felix M, Teixeira João C, de Filippo Cesare, Andrés Aida M
Abstract excerpt
Most human polymorphisms are neutral or slightly deleterious, but some genetic variation is advantageous and maintained in populations by balancing selection. Considered a rarity and overlooked for years, balanced polymorphisms have recently received renewed attention with several lines of evidence showing their relevance in human evolution. From theoretical work on its role in adaptation to empirical studies...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
