Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study.

Pharmacogenetics and genomics - 1 Nov 2014

Sørensen Izel F, Vazquez Ana I, Irvin Marguerite R, Sørensen Peter, Davis Barry R, Ford Charles E, Boerwinkle Eric, Eckfeldt John H, Arnett Donna K

Abstract excerpt

OBJECTIVE: The aim of this study was to investigate whether there is a genotype-by-treatment interaction in patients experiencing stroke and treated with one of three antihypertensive drugs, that is chlorthalidone, amlodipine, or lisinopril. PARTICIPANTS AND METHODS: A population of 436 African Americans and 539 whites who had experienced stroke in the GenHAT study were genotyped for 768 single nucleotide...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pharmacogenetics

Share to Polymorphism, Single Nucleotide

Share to Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 25171760
DOI: 10.1097/FPC.0000000000000088
PMCID: PMC4189974

Genes

NINJ2
PRICKLE1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacogenetic effects of 'candidate gene complexes' on stroke in the GenHAT study.PMID 25171760Read ↗

Pharmacogenomics in Stroke and Cardiovascular Disease: State of the ArtSemantic proximity Read ↗

Pharmacogenetic association of NOS3 variants with cardiovascular disease in patients with hypertension: the GenHAT study.Semantic proximity Read ↗

Effects of Genetic Variants on Stroke Risk.Semantic proximity Read ↗

Pharmacogenetic association of the NPPA T2238C genetic variant with cardiovascular disease outcomes in patients with hypertension.Semantic proximity Read ↗

The effects of genes implicated in cardiovascular disease on blood pressure response to treatment among treatment-naive hypertensive African Americans in the GenHAT study.Semantic proximity Read ↗

Gene panels to help identify subgroups at high and low risk of coronary heart disease among those randomized to antihypertensive treatment: the GenHAT study.Semantic proximity Read ↗

Evaluation of the interactions of common genetic mutations in stroke.Semantic proximity Read ↗

Impact of genetic testing on complex diseases.Semantic proximity Read ↗

Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke.Semantic proximity Read ↗

Interactions between the single nucleotide polymorphisms in the homocysteine pathway (MTHFR 677C>T, MTHFR 1298 A>C, and CBSins) and the efficacy of HMG-CoA reductase inhibitors in preventing cardiovascular disease in high-risk patients of hypertension: the GenHAT study.Semantic proximity Read ↗

Genetically proxied antidiabetic drugs targets and stroke riskSemantic proximity Read ↗

Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.