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Article

Genetically proxied antidiabetic drugs targets and stroke risk

30 Sept 2023

Abstract excerpt

BACKGROUND: Previous studies have assessed the association between antidiabetic drugs and stroke risk, but the results are inconsistent. Mendelian randomization (MR) was used to assess effects of antidiabetic drugs on stroke risk. METHODS: We selected blood glucose-lowering variants in genes encoding antidiabetic drugs targets from genome-wide association studies (GWAS). A two-sample MR and Colocalization...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37777789
DOI: 10.1186/s12967-023-04565-x

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