Article
Immuno-genomic profiling of patients with inflammatory bowel disease: a systematic review of genetic and functional in vivo studies of implicated genes.
Inflammatory bowel diseases - 1 Oct 2014
Coelho Tracy, Andreoletti Gaia, Ashton James J, Pengelly Reuben J, Gao Yifang, RamaKrishnan Ananth, Batra Akshay, Beattie Robert M, Williams Anthony P, Ennis Sarah
Abstract excerpt
BACKGROUND: Over the last 2 decades, there has been an ever-expanding catalog of genetic variants implicated in inflammatory bowel disease (IBD) through genome-wide association studies and next generation sequencing. In this article, we highlight the remarkable developments in understanding the genetic and immunological basis of IBD. The main objective of the study was to perform a systematic review of published...
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