Article
Serum mannose-binding lectin concentration, but not genotype, is associated with Clostridium difficile infection recurrence: a prospective cohort study.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Nov 2014
Swale Andrew, Miyajima Fabio, Kolamunnage-Dona Ruwanthi, Roberts Paul, Little Margaret, Beeching Nicholas J, Beadsworth Mike B J, Liloglou Triantafillos, Pirmohamed Munir
Abstract excerpt
BACKGROUND: Mannose-binding lectin (MBL) plays a key role in the activation of the lectin-complement pathway of innate immunity, and its deficiency has been linked with several acute infections. However, its role in predisposing to, or modulating disease severity in, Clostridium difficile infection (CDI) has not been investigated. METHODS: We prospectively recruited 308 CDI case patients and 145 control patients...
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