Article
Mannose-binding lectin genotype influences frequency and duration of infectious complications in children with malignancy.
Journal of pediatric hematology/oncology - 1 Jan 2013
Dommett Rachel, Chisholm Julia, Turner Malcolm, Bajaj-Elliott Mona, Klein Nigel J
Abstract excerpt
Children with cancer receiving identical treatment differ in their experience of infection, suggesting that variations in immunity may influence susceptibility to infection. Studies of the influence of mannose-binding lectin (MBL), an important component of the innate immune system, in children with febrile neutropenia (FN) have yielded conflicting results. We examined the role of MBL in infection susceptibility...
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