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Article

Genome-wide DNA methylation patterns in LSH mutant reveals de-repression of repeat elements and redundant epigenetic silencing pathways.

Genome research - 1 Oct 2014

Yu Weishi, McIntosh Carl, Lister Ryan, Zhu Iris, Han Yixing, Ren Jianke, Landsman David, Lee Eunice, Briones Victorino, Terashima Minoru, Leighty Robert, Ecker Joseph R, Muegge Kathrin

Abstract excerpt

Cytosine methylation is critical in mammalian development and plays a role in diverse biologic processes such as genomic imprinting, X chromosome inactivation, and silencing of repeat elements. Several factors regulate DNA methylation in early embryogenesis, but their precise role in the establishment of DNA methylation at a given site remains unclear. We have generated a comprehensive methylation map in...

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Identifiers

PMID: 25170028
DOI: 10.1101/gr.172015.114
PMCID: PMC4199375

Genes

HELLS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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