Article
Hyperpolarized 13C MR for molecular imaging of prostate cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine - 1 Oct 2014
Wilson David M, Kurhanewicz John
Abstract excerpt
Hyperpolarization using dissolution dynamic nuclear polarization has emerged as a versatile method to dramatically improve the MR signal of low-sensitivity nuclei. This technique facilitates the study of real-time metabolism in vitro and in vivo using (13)C-enriched substrates and has been applied to numerous models of human disease. In particular, several mechanisms underlying prostate cancer have been...
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