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Hyperpolarized [1- 13 C]pyruvate NMR spectroscopy reveals transition of tumor energy metabolism in tiny multicellular spheroids

2025-01-31

Abstract excerpt

<title>Abstract</title> Hyperpolarized (HP) [1-13C]pyruvate nuclear magnetic resonance (NMR) spectroscopy was employed to investigate tumor energy metabolism in tiny multicellular spheroids, serving as a model of early-phase tumorigenesis <italic>in vivo</italic>. A three-dimensional static culture of murine squamous cell carcinoma (SCCVII) cells formed uniform smaller multicellular spheroids (~ 150...

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Literature Corpus work: c671f4d5-46e1-5a18-af3b-72dc3150159a
DOI: 10.21203/rs.3.rs-5900705/v1

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